Selank
Selank is a synthetic heptapeptide analog of the endogenous tetrapeptide tuftsin, known for its anxiolytic, neuroprotective, and cognitive-enhancing properties. Developed in Russia, Selank has been extensively studied for its effects on anxiety modulation, immune system regulation, and cognitive function, without the sedative or addictive effects associated with traditional anxiolytics.
Overview
Selank is a seven-amino-acid peptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) that functions as a regulatory peptide in the central nervous system. Research indicates that it may modulate the expression of neurotrophins such as brain-derived neurotrophic factor (BDNF) and influence the balance of neurotransmitters, including serotonin and dopamine. Selank is also suggested to interact with the immune system, potentially supporting anti-inflammatory pathways and adaptive immune responses.
- Anxiolytic effects without sedation
- Potential cognitive enhancement, including improved memory and attention
- Supports neuroprotective mechanisms and neuronal plasticity
- May modulate immune response and reduce inflammation
Specifications
- Peptide Length: 7 amino acids
- Molecular Formula: C33H57N11O9
- Molecular Weight: 814.91 g/mol
- Other Names: Thr-Lys-Pro-Arg-Pro-Gly-Pro, Selank Peptide
Research and Clinical Studies
Anxiolytic and Anti-Stress Effects
Studies in animal and human models indicate that Selank may reduce anxiety and stress levels by modulating neurotransmitter systems, particularly serotonin and GABAergic pathways. Unlike traditional anxiolytics such as benzodiazepines, Selank does not induce sedation or dependency, making it a potentially safer alternative for anxiety management in research settings.
Cognitive Function and Memory
Preclinical studies suggest that Selank may enhance learning, memory consolidation, and attention span. These effects are believed to be mediated through upregulation of neurotrophins like BDNF, which support synaptic plasticity and neuronal communication. Research also indicates potential neuroprotective effects under conditions of cognitive stress or brain injury.
Immune System Modulation
Selank has been observed to influence cytokine expression and immune signaling pathways, suggesting possible anti-inflammatory and immunoregulatory actions. These effects are consistent with tuftsin-like peptides, which naturally regulate immune responses and support homeostasis in the central nervous system.
Usage Considerations
Selank is intended strictly for research and laboratory purposes. It is not approved for therapeutic use in humans outside of controlled studies. Proper laboratory handling, storage, and safety protocols should be followed when using this peptide.
Note: Selank peptide is available for research purposes only. Please review and adhere to all applicable Terms and Conditions before ordering.





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