MELANOTAN-I 10MG

Melanotan I

Melanotan I, also known as Afamelanotide, is a synthetic analog of the naturally occurring α-melanocyte-stimulating hormone (α-MSH). It has been extensively studied for its ability to stimulate melanogenesis, enhance skin pigmentation, and provide potential photoprotective effects. Unlike Melanotan II, Melanotan I primarily focuses on skin pigmentation with minimal influence on sexual function.

Overview

Melanotan I is a linear peptide that acts on melanocortin receptors, particularly MC1R, which regulates melanin production in melanocytes. By increasing melanin synthesis, Melanotan I may provide a natural tanning effect while potentially protecting skin against ultraviolet (UV) radiation-induced damage. It has also been explored for its potential to reduce the risk of sunburn and photodamage.

• Stimulates melanin production for enhanced skin pigmentation
• May provide photoprotective effects against UV radiation
• Primarily targets MC1R melanocortin receptors in melanocytes
• Studied in research for skin disorders, pigmentation enhancement, and photoprotection

Specifications

• Peptide Length: 13 amino acids
• Molecular Formula: C₅₉H₈₈N₁₈O₁₃
• Molecular Weight: 1600.86 g/mol
• Other Names: Afamelanotide, MT-1, Melanotan I analog

Research and Clinical Insights

Skin Pigmentation and Tanning

Melanotan I binds to MC1R receptors on melanocytes, stimulating melanin synthesis and leading to darker skin pigmentation. Research suggests it may produce a more even tan compared to natural UV-induced tanning, potentially reducing the risk of sunburn. It has been investigated for use in conditions such as erythropoietic protoporphyria, a disorder characterized by photosensitivity.

Photoprotection and UV Defense

Studies indicate that increased melanin production from Melanotan I may provide photoprotective benefits. By absorbing UV radiation, melanin reduces DNA damage in skin cells and may help prevent sunburn and photoaging. Preclinical and clinical research supports its potential as a protective agent against UV-induced oxidative stress.

Mechanism of Action

Melanotan I exerts its effects through activation of MC1R receptors, leading to increased cyclic AMP (cAMP) signaling within melanocytes. This triggers the enzymatic cascade responsible for melanin production, enhancing pigmentation and potentially improving skin resilience to UV exposure.

Safety and Usage Considerations

Melanotan I is intended strictly for research and laboratory purposes. It is not approved for general therapeutic use outside of controlled studies. Reported side effects in research settings include mild nausea, flushing, and transient headache. Proper handling, storage, and laboratory safety protocols should be strictly followed when using this peptide.

Note: Melanotan I (Afamelanotide) peptide is available for research purposes only. Please review and adhere to all applicable Terms and Conditions before ordering.