ARA-290 10MG
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$45.00
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ARA-290
ARA-290 is a synthetic peptide derived from the B-domain of erythropoietin (EPO) and is specifically engineered to activate tissue-protective erythropoietin receptors without inducing erythropoiesis. This selective activity allows ARA-290 to modulate anti-inflammatory pathways, promote tissue repair, and enhance cellular survival, making it a key focus in regenerative and metabolic research.
ARA-290 is actively investigated in experimental models for its cytoprotective effects, neuroprotection, anti-inflammatory signaling, and tissue repair potential across various organ systems, including the cardiovascular, nervous, and renal systems.
Overview
ARA-290 binds to the heterodimeric tissue-protective EPO receptor (TPR) complex, activating intracellular pathways such as PI3K/Akt and JAK/STAT without stimulating red blood cell production. This selective receptor engagement promotes anti-apoptotic signaling, reduces oxidative stress, and modulates inflammatory responses, supporting tissue survival under stress or injury conditions.
Through these mechanisms, ARA-290 is a valuable tool in research focused on neuroprotection, cardiovascular repair, metabolic resilience, and regenerative medicine.
- Activates tissue-protective erythropoietin receptors without stimulating erythropoiesis
- Reduces oxidative stress and inflammatory signaling
- Enhances tissue repair, cell survival, and regenerative processes
- Investigated in neuroprotective, cardiovascular, and renal research
- Supports studies of metabolic regulation, tissue resilience, and cytoprotection
Specifications
- Peptide Type: Tissue-protective EPO-derived peptide
- Amino Acid Length: 11 amino acids
- Molecular Formula: C58H92N18O14S
- Molecular Weight: ~1310 Da
- Other Names: ARA 290, EPO-Derived Cytoprotective Peptide
Research and Clinical Insights
Neuroprotective Effects
ARA-290 has been shown in experimental models to protect neurons from apoptosis, reduce oxidative damage, and enhance survival signaling. These properties make it a valuable compound in studies of neuropathic injury, neurodegeneration, and central nervous system resilience.
Anti-Inflammatory and Cytoprotective Activity
ARA-290 modulates inflammatory pathways by inhibiting pro-inflammatory cytokine release and promoting anti-inflammatory signaling. This dual action supports tissue survival in conditions of injury or metabolic stress.
Tissue Repair and Regeneration
Experimental studies indicate that ARA-290 promotes tissue repair and regeneration in cardiovascular, renal, and peripheral tissues. Its selective activation of the tissue-protective EPO receptor allows enhanced cell survival and accelerated healing without the hematopoietic effects of traditional EPO.
Metabolic and Organ System Research
ARA-290 is actively studied for its potential in metabolic and systemic organ protection, including effects on glucose regulation, cardiovascular resilience, and renal tissue preservation. Its cytoprotective properties make it a versatile research tool for regenerative medicine applications.
Usage Considerations
ARA-290 is supplied strictly for research and laboratory use. It is not approved for human therapeutic application. All handling, storage, and experimental procedures must follow institutional safety standards and regulatory guidelines.
Notice: ARA-290 is provided for research purposes only. Please review and adhere to all Terms and Conditions prior to ordering.
| Size | 5 MG, 10 MG |
|---|
ARA-290
ARA-290 is a synthetic peptide derived from the B-domain of erythropoietin (EPO) and is specifically engineered to activate tissue-protective erythropoietin receptors without inducing erythropoiesis. This selective activity allows ARA-290 to modulate anti-inflammatory pathways, promote tissue repair, and enhance cellular survival, making it a key focus in regenerative and metabolic research.
ARA-290 is actively investigated in experimental models for its cytoprotective effects, neuroprotection, anti-inflammatory signaling, and tissue repair potential across various organ systems, including the cardiovascular, nervous, and renal systems.
Overview
ARA-290 binds to the heterodimeric tissue-protective EPO receptor (TPR) complex, activating intracellular pathways such as PI3K/Akt and JAK/STAT without stimulating red blood cell production. This selective receptor engagement promotes anti-apoptotic signaling, reduces oxidative stress, and modulates inflammatory responses, supporting tissue survival under stress or injury conditions.
Through these mechanisms, ARA-290 is a valuable tool in research focused on neuroprotection, cardiovascular repair, metabolic resilience, and regenerative medicine.
- Activates tissue-protective erythropoietin receptors without stimulating erythropoiesis
- Reduces oxidative stress and inflammatory signaling
- Enhances tissue repair, cell survival, and regenerative processes
- Investigated in neuroprotective, cardiovascular, and renal research
- Supports studies of metabolic regulation, tissue resilience, and cytoprotection
Specifications
- Peptide Type: Tissue-protective EPO-derived peptide
- Amino Acid Length: 11 amino acids
- Molecular Formula: C58H92N18O14S
- Molecular Weight: ~1310 Da
- Other Names: ARA 290, EPO-Derived Cytoprotective Peptide
Research and Clinical Insights
Neuroprotective Effects
ARA-290 has been shown in experimental models to protect neurons from apoptosis, reduce oxidative damage, and enhance survival signaling. These properties make it a valuable compound in studies of neuropathic injury, neurodegeneration, and central nervous system resilience.
Anti-Inflammatory and Cytoprotective Activity
ARA-290 modulates inflammatory pathways by inhibiting pro-inflammatory cytokine release and promoting anti-inflammatory signaling. This dual action supports tissue survival in conditions of injury or metabolic stress.
Tissue Repair and Regeneration
Experimental studies indicate that ARA-290 promotes tissue repair and regeneration in cardiovascular, renal, and peripheral tissues. Its selective activation of the tissue-protective EPO receptor allows enhanced cell survival and accelerated healing without the hematopoietic effects of traditional EPO.
Metabolic and Organ System Research
ARA-290 is actively studied for its potential in metabolic and systemic organ protection, including effects on glucose regulation, cardiovascular resilience, and renal tissue preservation. Its cytoprotective properties make it a versatile research tool for regenerative medicine applications.
Usage Considerations
ARA-290 is supplied strictly for research and laboratory use. It is not approved for human therapeutic application. All handling, storage, and experimental procedures must follow institutional safety standards and regulatory guidelines.
Notice: ARA-290 is provided for research purposes only. Please review and adhere to all Terms and Conditions prior to ordering.
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