Melanotan II Peptide
Melanotan II is a synthetic peptide analog of the naturally occurring α-melanocyte-stimulating hormone (α-MSH). It has been extensively studied for its potential role in stimulating melanogenesis (melanin production), promoting skin tanning, and influencing sexual function and appetite regulation. Melanotan II interacts with melanocortin receptors in the body, which are involved in pigmentation, sexual arousal, and energy homeostasis.
Overview
Melanotan II is a cyclic heptapeptide derived from the α-MSH sequence. It primarily binds to melanocortin receptors, including MC1R, which regulates skin pigmentation, and MC3R/MC4R, which are associated with appetite, sexual arousal, and energy balance. Research indicates that Melanotan II can induce melanin synthesis in melanocytes, potentially leading to skin tanning without direct UV exposure, while also affecting sexual function through central nervous system pathways.
- Promotes melanin production and skin tanning
- May influence sexual arousal and libido
- Modulates appetite and energy balance
- Primarily used in research related to pigmentation and melanocortin receptor activity
Specifications
- Peptide Length: 7 amino acids (cyclic heptapeptide)
- Molecular Formula: C50H69N15O9
- Molecular Weight: 1025.21 g/mol
- Other Names: MT-II, Melanotan II, Melanotan II analog
Research and Clinical Insights
Skin Pigmentation and Tanning
Melanotan II binds to MC1R receptors in melanocytes, stimulating melanin production and promoting skin pigmentation. Preclinical studies indicate that it may induce skin tanning without direct exposure to ultraviolet (UV) radiation. The peptide has been studied for its potential protective effects against UV-induced skin damage.
Sexual Function and Libido
Research suggests that Melanotan II may influence sexual arousal by activating central melanocortin receptors (MC3R and MC4R) in the hypothalamus. Clinical studies have demonstrated that the peptide may increase sexual desire and responsiveness in both male and female subjects under controlled conditions.
Appetite and Energy Regulation
Melanotan II has been investigated for its effects on appetite and energy homeostasis. Activation of melanocortin receptors in the central nervous system may lead to reduced food intake and enhanced energy expenditure in animal models, though human studies are limited.
Safety and Usage Considerations
Melanotan II is intended strictly for research and laboratory purposes. It is not approved for general therapeutic use or self-administration. Reported side effects in clinical and preclinical studies include nausea, flushing, and mild changes in blood pressure. Proper laboratory handling, storage, and safety protocols must be followed when using this peptide.
Note: Melanotan II peptide is available for research purposes only. Please review and adhere to all applicable Terms and Conditions before ordering.





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